Having understood what gout disease is, it is also important to know causes of gout. Knowing the essential gout causes can help in proper diagnosis and eradication of this disease from the roots. There are several individual reasons behind causes of gout, and it is highly significant to determine each factor individually and prescribe appropriate treatment for each cause.
Gout is a complex human body disorder, and an abnormal increase in uric acid formation in the blood is causes of gout or Hyperuricemia. Purine is a chemical content in the body that decomposes to produce uric acid in blood. This generally comes as a part of high-purine food items that is broken down in the body in normal metabolism system. However, high intake of purine consumption and an improper metabolism system and kidney dysfunction can cause excessive production of uric acid, and cannot be excreted out essentially from the body. This is one of the main reasons what causes gout, as the surplus uric acid builds up around the joints of the body, resulting into sharp urate crystals in and around the muscle joints. This causes intense painful attacks and swelling inflammation in the joint areas. This is the preliminary symptom of any gout disorder in human body.
However, there are several other reasons behind causes of gout in human body, especially men. One such important cause can be traced back to genetics or the genetic disorders that you inherit from your parents or family. Several researches on genetics, as one of the integral reasons behind what causes gout, have essentially reported about 20% chances of developing gout syndrome if your parents or the family has a history of Hyperuricemia or other kidney disorder syndrome. Gout is not contagious but the disease can flow into the bloods from generation to generation causing abnormal uric acid production in blood, and subsequent painful gout attacks.
Lifestyle and nutrition also plays a significant role in causes of gout, and a poor living habit and lifestyle conditions are more prone to gout disease. Alcohol consumption, especially beer, and other high calorie and protein intakes substantially increases the risk of gout in human body. Moreover, the trauma and stress prevalent in modern lifestyle are also important essentials behind what causes gout. This is why the British people are found to be more likely in developing gout as compared to other people maintaining a moderate and somewhat balanced lifestyle.
Gender also plays a key role in causes of gout, because it has been found that men are more likely to fall victim of gout syndrome much earlier and in more numbers as compared to women. This is because men hormonal changes during puberty causes excessive metabolism of uric acid than compared to women. It is also the reason for what causes gout in men much earlier than women.
Understanding causes of gout essentially involves analyzing the medicinal factors and health conditions that results in increased formation of uric acid in blood. Certain surgery, physical and mental trauma, chronic fatigue syndrome, obesity and high blood pressure, chemotherapy conditions, dehydration and prolonged starvation can causes hormonal imbalances and improper metabolism system that causes a substantial rise in uric acid build up in the body. Chronic kidney disorder and other diseases like psoriasis, myeloma, tumors, hypothyroidism, hemolytic anemia, Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome are other important reasons behind what causes gout and excessive uric acid formation. While this is one of the significant reasons behind understanding causes of gout, there are several other medications and drugs that elevate the chances of Hyperuricemia in the blood.
• Regular consumption of medicines like diuretics and other anti-hypersensitive drugs can cause increase uric acid metabolism
• Transplant medicines like Cyclosporine A
• Aspirin (Ecotrin and Bayer)
• Probenecid (Benemid) and Allopurinol (Zyloprim) drugs
• Nicotinic acid content medicines like Niacin SR, Slo-Niacin, B3-500-Gr, Niaspan ER, etc.
Obesity or fast loss in weight, highly low calories diet and increased exposure to lead in the environment also play key roles in causes of gout in human body, and subsequent inflammation and acute arthritis attacks. Understanding and eliminating the main reasons behind causes of gout can essentially help in effective gout treatment with proper medication and dietary compliments.