Gout is a form of arthritis that is caused by having too much uric acid in the blood. Gout is characterized by sudden short bouts of painful inflammation, swelling and redness. Over eight million people in the United States suffer with some degree of gout inflammation.
Gout attacks occur during the night and wake the patient from their sleep, resulting in a restless night’s sleep. The pain that accompanies the gout interferes with walking, household chores and everyday activities. Joint damage that is caused by repeated attacks can cause permanent disability, if not treated. Tophi, which are deposits of urate crystals from under the skin, may occur in hands, feet, wrists, ankles and ears, feeling like hard bumps. They become inflamed and swollen during gout attacks. Additional tophi growth may cause joint damage or even joint destruction. If left untreated, acute gout attacks, along with tophi can damage joint tissues and the joints may eventually come out of alignment and become completely immobile. Another lifestyle disruption results in kidney stones, as urate crystals form in the kidneys. This can affect the kidney function.
Medicine for Gout Treatment can be done in two stages. First, the pain, swelling, redness and inflammation are treated until the symptoms have gone away during an attack of gout. Then, after the inflammation has subsided, other medicines used for Gout Treatment may be used to reduce the uric acid level in the blood, reducing the frequency of future attacks. Drugs used to lower the uric acid levels should not be given until the gout attack is over. Beginning drugs during gout attacks can cause the movement of uric acid stored in another part of the body and make the attack worse. Long term Gout Treatment will depend on how high uric acid levels are and the frequency of attacks.
Drugs for Gout Treatment usually involve a combination of medicines .There are many classes of Drugs to be used for Gout Treatment. The main objective of drug treatment, during an acute attack is to reduce the pain and inflammation. NSAIDS consist of a large class of Drugs that reduce both pain and inflammation. The ones that are sold over the counter are the low doses while the higher doses are sold by prescriptions. NSAIDs can cause gastrointestinal side effects, such as diarrhea, nausea and stomach ulcers. Kidney and liver damage can result in rear cases. Colchicine prevents uric acid in the body by forming urate crystals and should be taken soon after onset of acute gout symptoms to prevent pain and swelling. Side effects include vomiting, diarrhea and, nausea. It is usually prescribed to patients who cannot take NASIDs.
Corticosteroids reduce inflammation and can be taken orally or injected into the affected joint. Side effects of prolonged use include diabetes, osteoporosis, cataracts, increased blood pressure and a high risk of infection. It is usually used for patients who cannot take NDAIDs and colchicines. Xanthine Oxidase Inhibitors decrease the amount of uric acid that the body produces. However, these Drugs may trigger an acute attack. Patients are usually prescribed a short dosage of colchicines when beginning Xanthine Oxidase Inhibitor. The Drug probenecid helps the kidneys remove uric acid from the blood. Side effects include upset, stomach, rash and kidney stones.